DNA Interactions with Transition Metal Complexes
Title
DNA Interactions with Transition Metal Complexes
Subject
Chemistry
Creator
Aponte, Ella
Jeziorski
Contributor
Wachter, Erin (Mentor)
Language
English
Abstract
Coordination complexes have exhibited significant anticancer activity through unique binding and interaction mechanisms with DNA, such as intercalation. A series of ruthenium(II) and iron(II) complexes were synthesized using polypyridyl ligands.The structure and properties of these coordination complexes were characterized using NMR spectroscopy and absorbance spectroscopy. Through absorbance spectroscopy, the interactions between the transition metal complexes and DNA were studied. The results from the DNA studies could yield information regarding the binding process of transition metal complexes with DNA.
Collection
Citation
Aponte, Ella and Jeziorski, “DNA Interactions with Transition Metal Complexes,” RICE (Research, Internships, and Creative Endeavors) Symposium, accessed April 29, 2024, https://ricecentrecollege.omeka.net/items/show/131.